Metformin: Metformin is an oral antidiabetic drug, is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. Metformin is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
Side Effects of Metformin
Metformin is usually well tolerated. Typical side effects include diarrhea, nausea, low levels of vitamin B-12, heartburn, abdominal pain and the general feeling of discomfort. It has a low risk of causing low blood sugar. The high blood lactic acid level is a concern if the drug is prescribed inappropriately and in overly high doses. It should not be applied to those with notable liver disease or kidney difficulties. While no clear outrage comes from use throughout pregnancy, insulin is usually preferred for gestational diabetes. It controls by reducing glucose production by the liver and enhancing the insulin sensitivity of body tissues.
Metformin Usual Adult Dosages for Diabetes Type 2
Immediate-release
Initial dosage: 500 mg orally twice a day or 850 mg orally once a day
Dosage titration: Progress in 500 mg weekly increases or 850 mg every 2 weeks as tolerated
Sustaining dosage: 2000 mg every day in divided dosages
Highest dosage: 2550 mg every day
Extended-release
Initial dosage: 500 to 1000 mg orally once a day
Dosage titration: Further in 500 mg weekly increases as tolerated
Sustaining dosage: 2000 mg every day
Highest dosage: 2500 mg every day
Preparations & Brand Name of Metformin
This product is available in the following dosage forms:
Tablets (extended release): 500, 750, and 1000 mg.
